WebWhen simvastatin or lovastatin are taken at the same time as grapefruit juice, the estimated reduction in LDL cholesterol is 48%, and in heart disease is 70%. If the … WebThis can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death. You should avoid the consumption of grapefruit or grapefruit juice during treatment with simvastatin.

Grapefruit Juice: Sweet, Sour, and Healthy - FruitSmart

WebHere are examples of some types of drugs that grapefruit juice can cause problems (interact) with: • Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin). • Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine). ... WebApr 2, 2015 · A: Certain classes of drugs — most notably statins — are metabolized (broken down) in your intestines by an enzyme called … how to remove odor from clothes properly

Lobac and simvastatin Interactions Checker - Drugs.com

WebSee the list of drugs that interact with Grapefruit. Includes information on severity of interaction and the level of evidence for it. Grapefruit Interactions BNF NICE WebGrapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below. [13] WebJul 15, 2007 · Additionally, one study cited by the authors showed that when simvastatin was taken 24 hours after ingestion of the same large volume (1,200 mL) of grapefruit juice, the effect of grapefruit... normal ammonia hepatic encephalopathy