High theophylline levels
WebJun 20, 2024 · High blood sugar (increased thirst, increased urination, hunger, dry mouth, drowsiness, blurred vision, weight loss) ... Low levels of theophylline and caffeine may indicate that the drug has not reached a therapeutic level for the individual tested and there is insufficient drug present to be effective. WebAnswer: A theophylline level is a measure of theophylline in the bloodstream. This is used to regulate the dose. A blood level between 5-15 µg/ml often gives good relief of symptoms …
High theophylline levels
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WebB. Estimate Mr B’s theophylline level at the time of fitting C. How long after stopping Nuelin will Mr B’s theophylline be within the therapeutic range? [Population data: clearance = 0.04 L/hr/kg & volume of distribution = 0.48 L/kg. CHF reduces theophylline clearance by 50%. F … WebTheophylline metabolism can be altered by a variety of abnormal physiologic states as well as by exogenous factors. Adult studies demonstrate a significant influence of dietary composition on theophylline biotransformation. ... Compared to the normal diet, high protein diet markedly decreased the half-life, and high carbohydrate diet greatly ...
WebJun 30, 2024 · Adults are may be given about 300-600mg of Theophylline per day depending on their condition. This amount is equivalent to the therapeutic dose which is between 10-20mg/L. If the amount of 25mg/L, it … WebOct 4, 2024 · In patients with theophylline overdose who are at high risk for theophylline-induced seizures, e.g., patients with acute overdoses and serum theophylline concentrations > 100 mcg/mL or chronic overdosage in patients > 60 years of age with serum theophylline concentrations > 30 mcg/mL, the need for anticonvulsant therapy should be anticipated ...
WebSafe levels for people taking theophylline are often 8 to 20 mcg/mL. Levels above 20 mcg/mL may be harmful and can happen if people take too many pills within a short time … WebSerum theophylline levels were measured in 23 consecutive asthmatics presenting to the ER in an acute attack. 15 (68%) had therapeutic levels (above 10 mcg/ml) and 2 had toxic levels (above 20 mcg/ml), prior to receiving the standard …
WebFactor which increase the half life include heart failure, cirrhosis, viral infection and drugs like cimetidine, ciprofloxacin, erythromycin and the oral contraceptive pill. The half life is decreased by smoking, heavy drinking and drugs like phenytoin, carbamazepine, rifampicin and barbiturates.
WebIn most individuals, a plasma-theophylline concentration of 10–20 mg/litre (55–110 micromol/litre) is required for satisfactory bronchodilation, although a lower plasma … ctool 접속기WebMar 18, 2010 · Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2-agonists became more widely used. cto of shopcluesWebFeb 26, 2013 · Theophylline increases histone deacetylase-2 (HDAC2) via inhibition of phosphoinositide-3-kinase-δ (PI3Kδ), which is activated by oxidative stress to phosphorylate and reduce HDAC2. HDAC2 deacetylates core histones that have been acetylated by the histone acetyltransferase (HAT) activity of coactivators, such as CREB-binding protein … cto of youtubeWebThe adverse effects of theophylline include: Gastrointestinal disorders such as nausea, vomiting, gastro-oesophageal reflux. Neurological disorders such as tremor, headache, dizziness, central nervous system stimulation, insomnia, and convulsion (rare). Psychiatric disorders such as anxiety. ctoolprofikeyWebPurpose: To evaluate prospectively whether serum theophylline concentrations of 25 mg/L and greater were predictable (and presumably preventable) by use of basic pharmacokinetic calculations. Design: Prospective study. Patients: Fifty-five patients with a serum theophylline concentration of at least 25.0 mg/L were evaluated initially and if subsequent … earth sandbox simulatorWebTheophylline levels In most individuals a plasma theophylline of between 10-20mg/litre is required for satisfactory bronchodilation; however, a lower plasma theophylline … ctoolfunWebHigh blood theophylline levels can lead to symptoms of toxicity (see below). Therefore, theophylline blood levels are monitored periodically during treatment to assure achievement of optimal and safe levels. The initial dose is 300-600 mg once daily or as a divided dose for 3 days. The maintenance dose is 400-600 mg daily. ctool 접속기 다운